The active ingredient in Yohimbe Ultimate Nutrition is yohimbine, a chemical contained in yohimbe bark. The National Institutes of Health states that yohimbine works as a sexual stimulant by increasing blood flow and nerve impulses to genitalia. The American Cancer Society reports that after analyzing a number of commercial over-the-counter yohimbe bark products, the Federal Drug Administration found most bark supplements contained little to no yohimbine. Yohimbe Ultimate Nutrition claims its yohimbe supplement contains 1 percent yohimbine per 800 mg tablet.
The Yohimbe Ultimate Nutrition product line stems from an evergreen tree native to Nigeria, Congo and other West African countries. The bark of the tree has been used historically in African folk medicine to promote sexual vitality as a natural aphrodisiac. The American Cancer Society states that in the US, the drug yohimbine hydrochloride is available by prescription as a treatment for erectile dysfunction and yohimbe supplements can be purchased through the Internet or in health food stores.